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首页>products>YAMATO>Bio-Technology Related Instrum> Details
Mapping Fluorescence Microphotometry System MapAnalyzer
 
 
 

In addition to conventional observation and photomicrographic techniques, the quantitative and qualitative analysis of specimen through microphotometry is more and more in demand. In the medical and biological fields, microphotometry is established technique for quantitative analysis of various intercellular substances.
MapAnalyzer was developed for quantitative microanalysis of distribution of various substances, such as neurotransmitters and neuromodulators, in the large tissue slice. With Yamato Scientific Co.�fs MapAnalyzer, the possibilities of your research will be extended.




Quantitative immunohistochemical distribution of substance P in a brain slice of an adult normal human (male, age 50). Data were obtained from approximately six million regions in the brain at 50-µm intervals. Conspicuously intense substance P-like immunoreactivity was observed in the internal segment of the globus pallidus. The immunoreactive intensity in the internal segment of the globus pallidus was approximately twice as high as that in the external segment of the globus pallidus.
(See, Neurosci. Res. 35: 339-346,1999)

Quantitative immunohistochemical distribution of tyrosine hydroxylase in the coronal slice of a rat brain. The stained slice was measured at 20-µm intervals, and the distribution of the intensity obtained from approximately 250,000 microareas is displayed. Markedly intense tyrosine hydroxylase-like immunoreactivity was distributed in the dorsolateral area of the neostriatum, nucleus accumbens, olfactory tubercle and motor cortex.
 

Specifications:
Model MapAnalyzer
Microscope Epi-fluorescence microscope
Photometry Fluorescence and Transmittance mode
Measuring spot Min. diameter: 20 µm on a slice (standard)
5 µm on a slice (option)
Light source Halogen lamp
Detector Photomultiplier tube
Scanning stage Motor-driven X-Y stage
Min. stepping movement: 1 µm, Max. stage motion: 140x140 mm
Scanning speed: 10 mm/s
Dark box Desktop type
Computer OS: Windows NT or Windows 2000
Software Newly developed software for automatic analysis
Save mode: CSV format or BMP file
Graphics: two-dimensional and three-dimensional display
 
 
 
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